Linking genotype to phenotype on beads: high throughput selection of peptides with biological function

Although peptides are well recognised biological molecules in vivo, their selection from libraries is challenging because of relative low affinity whilst in linear conformation. We hypothesized that multiplexed peptides and DNA on the surface of beads would provide a platform for enhanced avidity an...

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Detalles Bibliográficos
Autores principales: Huang, Li-Chieh, Pan, Xiaoyan, Yang, Hongbing, Wan, Lai Kin Derek, Stewart-Jones, Guillaume, Dorrell, Lucy, Ogg, Graham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805977/
https://www.ncbi.nlm.nih.gov/pubmed/24149829
http://dx.doi.org/10.1038/srep03030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3805977/
https://www.ncbi.nlm.nih.gov/pubmed/24149829
http://dx.doi.org/10.1038/srep03030

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