OX40 signaling favors the induction of T(H)9 cells and airway inflammation

The mechanisms regulating T helper 9 (T(H)9) cells and T(H)9-mediated diseases remain poorly defined. Here, we demonstrate that the receptor OX40 (Tnfrsf4) is a powerful inducer of T(H)9 cells in vitro and T(H)9-dependent airway inflammation in vivo. Under TGF-β based polarizing conditions, OX40 lig...

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Detalles Bibliográficos
Autores principales: Xiao, Xiang, Balasubramanian, Savithri, Liu, Wentao, Chu, Xiufeng, Wang, Haibin, Taparowsky, Elizabeth J., Fu, Yang-Xin, Choi, Yongwon, Walsh, Matthew C., Li, Xian Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806044/
https://www.ncbi.nlm.nih.gov/pubmed/22842344
http://dx.doi.org/10.1038/ni.2390

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806044/
https://www.ncbi.nlm.nih.gov/pubmed/22842344
http://dx.doi.org/10.1038/ni.2390

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