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OX40 signaling favors the induction of T(H)9 cells and airway inflammation
The mechanisms regulating T helper 9 (T(H)9) cells and T(H)9-mediated diseases remain poorly defined. Here, we demonstrate that the receptor OX40 (Tnfrsf4) is a powerful inducer of T(H)9 cells in vitro and T(H)9-dependent airway inflammation in vivo. Under TGF-β based polarizing conditions, OX40 lig...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806044/ https://www.ncbi.nlm.nih.gov/pubmed/22842344 http://dx.doi.org/10.1038/ni.2390 |