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Combination with Methotrexate and Cyclophosphamide Attenuated Maturation of Dendritic Cells: Inducing Treg Skewing and Th17 Suppression In Vivo

Immune disorder is considered the main pathogenesis of autoimmune diseases, such as rheumatoid arthritis (RA). The balance of the two special subsets of CD4(+)T cells, T helper cell 17 (Th17), and Regulator T cell (Treg) is the key factor of maintaining a normal immune response. Dendritic cells (DCs...

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Detalles Bibliográficos
Autores principales: Yu, Xiaoyang, Wang, Caihong, Luo, Jing, Zhao, Xiangcong, Wang, Lixing, Li, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806152/
https://www.ncbi.nlm.nih.gov/pubmed/24194771
http://dx.doi.org/10.1155/2013/238035