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Allosteric coupling of the inner activation gate to the outer pore of a potassium channel
In potassium channels, functional coupling of the inner and outer pore gates may result from energetic interactions between residues and conformational rearrangements that occur along a structural path between them. Here, we show that conservative mutations of a residue near the inner activation gat...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806241/ https://www.ncbi.nlm.nih.gov/pubmed/24149575 http://dx.doi.org/10.1038/srep03025 |