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Genome-wide identification of genes with amplification and/or fusion in small cell lung cancer

To obtain a landscape of gross genetic alterations in small cell lung cancer (SCLC), genome-wide copy number analysis and whole-transcriptome sequencing were performed in 58 and 42 SCLCs, respectively. Focal amplification of known oncogene loci, MYCL1 (1p34.2), MYCN (2p24.3), and MYC (8q24.21), was...

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Detalles Bibliográficos
Autores principales: Iwakawa, Reika, Takenaka, Masataka, Kohno, Takashi, Shimada, Yoko, Totoki, Yasushi, Shibata, Tatsuhiro, Tsuta, Koji, Nishikawa, Ryo, Noguchi, Masayuki, Sato-Otsubo, Aiko, Ogawa, Seishi, Yokota, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806277/
https://www.ncbi.nlm.nih.gov/pubmed/23716474
http://dx.doi.org/10.1002/gcc.22076