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Multiple Aspects of Gene Dysregulation in Huntington’s Disease

Huntington’s Disease (HD) is a genetic neurodegenerative disease caused by a CAG expansion in the gene encoding Huntingtin (Htt). It is characterized by chorea, cognitive, and psychiatric disorders. The most affected brain region is the striatum, and the clinical symptoms are directly correlated to...

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Detalles Bibliográficos
Autores principales: Moumné, Lara, Betuing, Sandrine, Caboche, Jocelyne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806340/
https://www.ncbi.nlm.nih.gov/pubmed/24167500
http://dx.doi.org/10.3389/fneur.2013.00127