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Molecular grading of tumors of the upper urothelial tract using FGFR3 mutation status identifies patients with favorable prognosis

BACKGROUND: Mutations in FGFR3 have been shown to occur in tumors of the upper urothelial tract and may be indicative of a good prognosis. In bladder tumors, the combination of FGFR3 mutation status and Ki-67 level has been used to define a tumor’s molecular grade and predict survival. Pathological...

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Detalles Bibliográficos
Autores principales: Lyle, Stephen R, Hsieh, Chung-Cheng, Fernandez, Cecilia A, Shuber, Anthony P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806446/
https://www.ncbi.nlm.nih.gov/pubmed/24199183
http://dx.doi.org/10.2147/RRU.S37355