Influence of Lipid A Acylation Pattern on Membrane Permeability and Innate Immune Stimulation

Lipid A, the hydrophobic anchor of lipopolysaccharide (LPS), is an essential component in the outer membrane of Gram-negative bacteria. It can stimulate the innate immune system via Toll-like receptor 4/myeloid differentiation factor 2 (TLR4/MD2), leading to the release of inflammatory cytokines. In...

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Detalles Bibliográficos
Autores principales: Li, Yanyan, Wang, Zhou, Chen, Jiuzhou, Ernst, Robert K., Wang, Xiaoyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806461/
https://www.ncbi.nlm.nih.gov/pubmed/24065161
http://dx.doi.org/10.3390/md11093197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806461/
https://www.ncbi.nlm.nih.gov/pubmed/24065161
http://dx.doi.org/10.3390/md11093197

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