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C-Peptide Activates AMPKα and Prevents ROS-Mediated Mitochondrial Fission and Endothelial Apoptosis in Diabetes

Vasculopathy is a major complication of diabetes; however, molecular mechanisms mediating the development of vasculopathy and potential strategies for prevention have not been identified. We have previously reported that C-peptide prevents diabetic vasculopathy by inhibiting reactive oxygen species...

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Detalles Bibliográficos
Autores principales: Bhatt, Mahendra Prasad, Lim, Young-Cheol, Kim, Young-Myeong, Ha, Kwon-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806599/
https://www.ncbi.nlm.nih.gov/pubmed/23884890
http://dx.doi.org/10.2337/db13-0039