Profilin-1 Haploinsufficiency Protects Against Obesity-Associated Glucose Intolerance and Preserves Adipose Tissue Immune Homeostasis

Metabolic inflammation may contribute to the pathogenesis of obesity and its comorbidities, including type 2 diabetes and cardiovascular disease. Previously, we showed that the actin-binding protein profilin-1 (pfn) plays a role in atherogenesis because pfn heterozygote mice (PfnHet) exhibited a sig...

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Detalles Bibliográficos
Autores principales: Romeo, Giulio R., Pae, Munkyong, Eberlé, Delphine, Lee, Jongsoon, Shoelson, Steven E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806603/
https://www.ncbi.nlm.nih.gov/pubmed/23884883
http://dx.doi.org/10.2337/db13-0050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806603/
https://www.ncbi.nlm.nih.gov/pubmed/23884883
http://dx.doi.org/10.2337/db13-0050

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