γ-Aminobutyric Acid Regulates Both the Survival and Replication of Human β-Cells

γ-Aminobutyric acid (GABA) has been shown to inhibit apoptosis of rodent β-cells in vitro. In this study, we show that activation of GABA(A) receptors (GABA(A)-Rs) or GABA(B)-Rs significantly inhibits oxidative stress–related β-cell apoptosis and preserves pancreatic β-cells in streptozotocin-render...

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Detalles Bibliográficos
Autores principales: Tian, Jide, Dang, Hoa, Chen, Zheying, Guan, Alice, Jin, Yingli, Atkinson, Mark A., Kaufman, Daniel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806626/
https://www.ncbi.nlm.nih.gov/pubmed/23995958
http://dx.doi.org/10.2337/db13-0931

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806626/
https://www.ncbi.nlm.nih.gov/pubmed/23995958
http://dx.doi.org/10.2337/db13-0931

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