Characterization of the Akt2 Domain Essential for Binding Nuclear p21cip1 to Promote Cell Cycle Arrest during Myogenic Differentiation

The binding of the cdk inhibitor p21cip1 to Akt2 in the nucleus is an essential component in determining the specific role of Akt2 in the cell cycle arrest that precedes myogenic differentiation. Here, through a combination of biochemical and cell biology approaches, we have addressed the molecular...

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Detalles Bibliográficos
Autores principales: Heron-Milhavet, Lisa, Franckhauser, Celine, Fernandez, Anne, Lamb, Ned J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806761/
https://www.ncbi.nlm.nih.gov/pubmed/24194853
http://dx.doi.org/10.1371/journal.pone.0076987

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806761/
https://www.ncbi.nlm.nih.gov/pubmed/24194853
http://dx.doi.org/10.1371/journal.pone.0076987

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