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Reversing the Intractable Nature of Pancreatic Cancer by Selectively Targeting ALDH-High, Therapy-Resistant Cancer Cells

Human pancreatic ductal adenocarcinoma (PDAC) is a cancer with a dismal prognosis. The efficacy of PDAC anticancer therapies is often short-lived; however, there is little information on how this disease entity so frequently gains resistance to treatment. We adopted the concept of cancer stem cells...

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Detalles Bibliográficos
Autores principales: Kim, Sang Kyum, Kim, Honsoul, Lee, Da-hye, Kim, Tae-shin, Kim, Tackhoon, Chung, Chaeuk, Koh, Gou Young, Kim, Hoguen, Lim, Dae-Sik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806801/
https://www.ncbi.nlm.nih.gov/pubmed/24194908
http://dx.doi.org/10.1371/journal.pone.0078130