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Energetic Contributions to Channel Gating of Residues in the Muscle Nicotinic Receptor β1 Subunit

In the pentameric ligand-gated ion channel family, transmitter binds in the extracellular domain and conformational changes result in channel opening in the transmembrane domain. In the muscle nicotinic receptor and other heteromeric members of the family one subunit does not contribute to the canon...

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Detalles Bibliográficos
Autores principales: Akk, Gustav, Eaton, Megan, Li, Ping, Zheng, Steven, Lo, Joshua, Steinbach, Joe Henry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806828/
https://www.ncbi.nlm.nih.gov/pubmed/24194945
http://dx.doi.org/10.1371/journal.pone.0078539