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A Rat Model of Hemidystonia Induced by 3-Nitropropionic Acid

OBJECTIVE: Secondary dystonia commonly presents as hemidystonia and is often refractory to current treatments. We aimed to establish an inducible rat model of hemidystonia utilizing 3-nitropropionic acid (3-NP) and to determine the pathophysiology of this model. METHODS: Two different doses of 3-NP...

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Detalles Bibliográficos
Autores principales: Liu, Huan-Guang, Ma, Yu, Meng, Da-Wei, Yang, An-Chao, Zhang, Jian-guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806852/
https://www.ncbi.nlm.nih.gov/pubmed/24194961
http://dx.doi.org/10.1371/journal.pone.0079199