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The Critical Role of DNA Extraction for Detection of Mycobacteria in Tissues
BACKGROUND: Nucleic acid-based methods offer promise for both targeted and exploratory investigations of microbes in tissue samples. As the starting material for such studies is a mixture of host and microbial DNA, we have critically evaluated the DNA extraction step to determine the quantitative an...
Autores principales: | Radomski, Nicolas, Kreitmann, Louis, McIntosh, Fiona, Behr, Marcel A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806855/ https://www.ncbi.nlm.nih.gov/pubmed/24194951 http://dx.doi.org/10.1371/journal.pone.0078749 |
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