High-Throughput 3D Screening Reveals Differences in Drug Sensitivities between Culture Models of JIMT1 Breast Cancer Cells

The traditional method for studying cancer in vitro is to grow immortalized cancer cells in two-dimensional monolayers on plastic. However, many cellular features are impaired in these artificial conditions, and large changes in gene expression compared to tumors have been reported. Three-dimensiona...

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Detalles Bibliográficos
Autores principales: Hongisto, Vesa, Jernström, Sandra, Fey, Vidal, Mpindi, John-Patrick, Kleivi Sahlberg, Kristine, Kallioniemi, Olli, Perälä, Merja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806867/
https://www.ncbi.nlm.nih.gov/pubmed/24194875
http://dx.doi.org/10.1371/journal.pone.0077232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806867/
https://www.ncbi.nlm.nih.gov/pubmed/24194875
http://dx.doi.org/10.1371/journal.pone.0077232

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