SIRT1 Deacetylates FOXA2 and Is Critical for Pdx1 Transcription and β-Cell Formation

Pancreas duodenum homeobox 1 (PDX1) is essential for pancreas development and β-cell formation; however more studies are needed to clearly illustrate the precise mechanism regarding spatiotemporal regulation of Pdx1 expression during β-cell formation and development. Here, we demonstrate that SIRT1,...

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Detalles Bibliográficos
Autores principales: Wang, Rui-Hong, Xu, Xiaoling, Kim, Hyun-Seok, Xiao, Zhen, Deng, Chu-Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3807017/
https://www.ncbi.nlm.nih.gov/pubmed/24163589
http://dx.doi.org/10.7150/ijbs.7529

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3807017/
https://www.ncbi.nlm.nih.gov/pubmed/24163589
http://dx.doi.org/10.7150/ijbs.7529

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