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SIRT1 Deacetylates FOXA2 and Is Critical for Pdx1 Transcription and β-Cell Formation
Pancreas duodenum homeobox 1 (PDX1) is essential for pancreas development and β-cell formation; however more studies are needed to clearly illustrate the precise mechanism regarding spatiotemporal regulation of Pdx1 expression during β-cell formation and development. Here, we demonstrate that SIRT1,...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Ivyspring International Publisher
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3807017/ https://www.ncbi.nlm.nih.gov/pubmed/24163589 http://dx.doi.org/10.7150/ijbs.7529 |