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Pathophysiological power of improper tonic GABAA conductances in mature and immature models

High-affinity extrasynaptic gamma-aminobutyric acid A (GABA(A)) receptors are tonically activated by low and consistent levels of ambient GABA, mediating chronic inhibition against neuronal excitability (tonic inhibition) and the modulation of neural development. Synaptic (phasic) inhibition is spat...

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Detalles Bibliográficos
Autores principales: Egawa, Kiyoshi, Fukuda, Atsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3807051/
https://www.ncbi.nlm.nih.gov/pubmed/24167475
http://dx.doi.org/10.3389/fncir.2013.00170