Cargando…
Ataxin-3 Is a Multivalent Ligand for the Parkin Ubl Domain
[Image: see text] The ubiquitin signaling pathway consists of hundreds of enzymes that are tightly regulated for the maintenance of cell homeostasis. Parkin is an E3 ubiquitin ligase responsible for conjugating ubiquitin onto a substrate protein, which itself can be ubiquitinated. Ataxin-3 performs...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical Society
2013
|
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3807529/ https://www.ncbi.nlm.nih.gov/pubmed/24063750 http://dx.doi.org/10.1021/bi400780v |