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Ataxin-3 Is a Multivalent Ligand for the Parkin Ubl Domain

[Image: see text] The ubiquitin signaling pathway consists of hundreds of enzymes that are tightly regulated for the maintenance of cell homeostasis. Parkin is an E3 ubiquitin ligase responsible for conjugating ubiquitin onto a substrate protein, which itself can be ubiquitinated. Ataxin-3 performs...

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Detalles Bibliográficos
Autores principales:	Bai, Jane J., Safadi, Susan S., Mercier, Pascal, Barber, Kathryn R., Shaw, Gary S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2013
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3807529/ https://www.ncbi.nlm.nih.gov/pubmed/24063750 http://dx.doi.org/10.1021/bi400780v

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