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Mechanistic Basis of Desmosome-Targeted Diseases

Desmosomes are dynamic junctions between cells that maintain the structural integrity of skin and heart tissues by withstanding shear forces. Mutations in component genes cause life-threatening conditions including arrhythmogenic right ventricular cardiomyopathy, and desmosomal proteins are targeted...

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Detalles Bibliográficos
Autores principales: Al-Jassar, Caezar, Bikker, Hennie, Overduin, Michael, Chidgey, Martyn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3807649/
https://www.ncbi.nlm.nih.gov/pubmed/23911551
http://dx.doi.org/10.1016/j.jmb.2013.07.035