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Structure of the CRISPR Interference Complex CSM Reveals Key Similarities with Cascade
The Clustered Regularly Interspaced Palindromic Repeats (CRISPR) system is an adaptive immune system in prokaryotes. Interference complexes encoded by CRISPR-associated (cas) genes utilize small RNAs for homology-directed detection and subsequent degradation of invading genetic elements, and they ha...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3807668/ https://www.ncbi.nlm.nih.gov/pubmed/24119402 http://dx.doi.org/10.1016/j.molcel.2013.08.020 |