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Structure of the CRISPR Interference Complex CSM Reveals Key Similarities with Cascade

The Clustered Regularly Interspaced Palindromic Repeats (CRISPR) system is an adaptive immune system in prokaryotes. Interference complexes encoded by CRISPR-associated (cas) genes utilize small RNAs for homology-directed detection and subsequent degradation of invading genetic elements, and they ha...

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Detalles Bibliográficos
Autores principales: Rouillon, Christophe, Zhou, Min, Zhang, Jing, Politis, Argyris, Beilsten-Edmands, Victoria, Cannone, Giuseppe, Graham, Shirley, Robinson, Carol V., Spagnolo, Laura, White, Malcolm F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3807668/
https://www.ncbi.nlm.nih.gov/pubmed/24119402
http://dx.doi.org/10.1016/j.molcel.2013.08.020