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Effect of P2X(4) and P2X(7) receptor antagonism on the pressure diuresis relationship in rats
Reduced glomerular filtration, hypertension and renal microvascular injury are hallmarks of chronic kidney disease, which has a global prevalence of ~10%. We have shown previously that the Fischer (F344) rat has lower GFR than the Lewis rat, and is more susceptible to renal injury induced by hyperte...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3807716/ https://www.ncbi.nlm.nih.gov/pubmed/24187541 http://dx.doi.org/10.3389/fphys.2013.00305 |