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Structure of an atypical periplasmic adaptor from a multidrug efflux pump of the spirochete Borrelia burgdorferi

Periplasmic adaptor proteins are essential components of bacterial tripartite multidrug efflux pumps. Here we report the 2.35 Å resolution crystal structure of the BesA adaptor from the spirochete Borrelia burgdorferi solved using selenomethionine derivatized protein. BesA shows the archetypal linea...

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Detalles Bibliográficos
Autores principales: Greene, Nicholas P., Hinchliffe, Philip, Crow, Allister, Ababou, Abdessamad, Hughes, Colin, Koronakis, Vassilis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science B.V 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3807786/
https://www.ncbi.nlm.nih.gov/pubmed/23851070
http://dx.doi.org/10.1016/j.febslet.2013.06.056