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Ipilimumab for advanced melanoma: A pharmacologic perspective

Ipilimumab, a fully human anti-CTLA-4 antibody, has been approved for the treatment of unresectable or metastatic melanoma based on its survival benefit demonstrated in randomized phase III studies. The current approved dosing schedule of ipilimumab is 3 mg/kg as a 90-min intravenous infusion every...

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Detalles Bibliográficos
Autores principales: Trinh, Van Anh, Hagen, Brenda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3807857/
https://www.ncbi.nlm.nih.gov/pubmed/23047236
http://dx.doi.org/10.1177/1078155212459100