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Ipilimumab for advanced melanoma: A pharmacologic perspective
Ipilimumab, a fully human anti-CTLA-4 antibody, has been approved for the treatment of unresectable or metastatic melanoma based on its survival benefit demonstrated in randomized phase III studies. The current approved dosing schedule of ipilimumab is 3 mg/kg as a 90-min intravenous infusion every...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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SAGE Publications
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3807857/ https://www.ncbi.nlm.nih.gov/pubmed/23047236 http://dx.doi.org/10.1177/1078155212459100 |