Microbial colonization influences early B-lineage development in the gut lamina propria

The RAG1/RAG2 endonuclease ("RAG") initiates the V(D)J recombination reaction that assembles Ig heavy (IgH) and light (IgL) chain variable region exons from germline gene segments to generate primary antibody repertoires(1). IgH V(D)J assembly occurs in progenitor (pro-) B cells followed b...

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Detalles Bibliográficos
Autores principales: Wesemann, Duane R., Portuguese, Andrew J., Meyers, Robin M., Gallagher, Michael P., Cluff-Jones, Kendra, Magee, Jennifer M., Panchakshari, Rohit A., Rodig, Scott J., Kepler, Thomas B., Alt, Frederick W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3807868/
https://www.ncbi.nlm.nih.gov/pubmed/23965619
http://dx.doi.org/10.1038/nature12496

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3807868/
https://www.ncbi.nlm.nih.gov/pubmed/23965619
http://dx.doi.org/10.1038/nature12496

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