Cargando…

Ethyl cellulose and hydroxypropyl methyl cellulose buoyant microspheres of metoprolol succinate: Influence of pH modifiers

INTRODUCTION: Incorporation of pH modifier has been the usual strategy employed to enhance the dissolution of weakly basic drug from floating microspheres. Microspheres prepared using a combination of both ethyl cellulose (EC) and hydroxypropyl methylcellulose (HPMC) which shows highest release were...

Descripción completa

Detalles Bibliográficos
Autores principales: Raut, Neha S, Somvanshi, Sachin, Jumde, Amol B, Khandelwal, Harsha M, Umekar, Milind J, Kotagale, Nandkishor Ramdas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3807984/
https://www.ncbi.nlm.nih.gov/pubmed/24167789
http://dx.doi.org/10.4103/2230-973X.119235