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Caspase 1-mediated regulation of fibrogenesis in diet-induced steatohepatitis

Nonalcoholic steatohepatitis (NASH) is typically associated with pro-apoptotic caspase activation. A potential role for pro-inflammatory caspases remains incompletely understood. Our aims were to examine a potential role of caspase 1 in the development of liver damage and fibrosis in NASH. C57BL/6 w...

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Detalles Bibliográficos
Autores principales: Dixon, Laura, Berk, Michael, Thapaliya, Samjhana, Papouchado, Bettina G., Feldstein, Ariel E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3808241/
https://www.ncbi.nlm.nih.gov/pubmed/22411067
http://dx.doi.org/10.1038/labinvest.2012.45