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Dectin-2-Dependent NKT Cell Activation and Serotype-Specific Antibody Production in Mice Immunized with Pneumococcal Polysaccharide Vaccine

Although thymus-independent type 2 antigens generally do not undergo Ig class switching from IgM to IgG, pneumococcal polysaccharide vaccine (PPV) induces the production of serotype-specific IgG. How this happens remains unclear, however. In the present study, PPV immunization induced production of...

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Detalles Bibliográficos
Autores principales: Miyasaka, Tomomitsu, Akahori, Yukiko, Toyama, Masahiko, Miyamura, Namiko, Ishii, Keiko, Saijo, Shinobu, Iwakura, Yoichiro, Kinjo, Yuki, Miyazaki, Yoshitsugu, Oishi, Kazunori, Kawakami, Kazuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3808275/
https://www.ncbi.nlm.nih.gov/pubmed/24205278
http://dx.doi.org/10.1371/journal.pone.0078611