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Integrative Pathway-Based Approach for Genome-Wide Association Studies: Identification of New Pathways for Rheumatoid Arthritis and Type 1 Diabetes

Genome-wide association studies (GWAS) led to the identification of numerous novel loci for a number of complex diseases. Pathway-based approaches using genotypic data provide tangible leads which cannot be identified by single marker approaches as implemented in GWAS. The available pathway analysis...

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Detalles Bibliográficos
Autores principales: Büchel, Finja, Mittag, Florian, Wrzodek, Clemens, Zell, Andreas, Gasser, Thomas, Sharma, Manu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3808349/
https://www.ncbi.nlm.nih.gov/pubmed/24205270
http://dx.doi.org/10.1371/journal.pone.0078577