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Filamin-A Regulates Neutrophil Uropod Retraction through RhoA during Chemotaxis
Filamin-A (FLNa) has been shown to be a key cross-linker of actin filaments in the leading edge of a motile melanoma cell line, however its role in neutrophils undergoing chemotaxis is unknown. Using a murine transgenic model in which FLNa is selectively deleted in granulocytes, we report that, whil...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3808352/ https://www.ncbi.nlm.nih.gov/pubmed/24205360 http://dx.doi.org/10.1371/journal.pone.0079009 |