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Hyperuricemia Causes Pancreatic β-Cell Death and Dysfunction through NF-κB Signaling Pathway

Accumulating clinical evidence suggests that hyperuricemia is associated with an increased risk of type 2 diabetes. However, it is still unclear whether elevated levels of uric acid can cause direct injury of pancreatic β-cells. In this study, we examined the effects of uric acid on β-cell viability...

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Detalles Bibliográficos
Autores principales: Jia, Lu, Xing, Jing, Ding, Ying, Shen, Yachen, Shi, Xuhui, Ren, Wei, Wan, Meng, Guo, Jianjin, Zheng, Shujing, Liu, Yun, Liang, Xiubin, Su, Dongming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3808354/
https://www.ncbi.nlm.nih.gov/pubmed/24205181
http://dx.doi.org/10.1371/journal.pone.0078284