Cargando…

Polymorphic Sites at the 3’ Untranslated Region of the HLA-G Gene Are Associated with Differential hla-g Soluble Levels in the Brazilian and French Population

HLA-G molecule has well-recognized tolerogenic properties, and the encoding gene shows lower frequency of polymorphism at the coding region but higher variability at regulatory 5’ and 3’ untranslated (3’UTR) regions. At least three 3’UTR polymorphic sites have been associated with HLA-G mRNA regulat...

Descripción completa

Detalles Bibliográficos
Autores principales: Martelli-Palomino, Gustavo, Pancotto, Joao A., Muniz, Yara C., Mendes-Junior, Celso T., Castelli, Erick C., Massaro, Juliana D., Krawice-Radanne, Irene, Poras, Isabelle, Rebmann, Vera, Carosella, Edgardo D., Rouas-Freiss, Nathalie, Moreau, Philippe, Donadi, Eduardo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3808361/
https://www.ncbi.nlm.nih.gov/pubmed/24204558
http://dx.doi.org/10.1371/journal.pone.0071742