MicroRNA-200c Modulates the Expression of MUC4 and MUC16 by Directly Targeting Their Coding Sequences in Human Pancreatic Cancer

Transmembrane mucins, MUC4 and MUC16 are associated with tumor progression and metastatic potential in human pancreatic adenocarcinoma. We discovered that miR-200c interacts with specific sequences within the coding sequence of MUC4 and MUC16 mRNAs, and evaluated the regulatory nature of this associ...

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Detalles Bibliográficos
Autores principales: Radhakrishnan, Prakash, Mohr, Ashley M., Grandgenett, Paul M., Steele, Maria M., Batra, Surinder K., Hollingsworth, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3808362/
https://www.ncbi.nlm.nih.gov/pubmed/24204560
http://dx.doi.org/10.1371/journal.pone.0073356

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3808362/
https://www.ncbi.nlm.nih.gov/pubmed/24204560
http://dx.doi.org/10.1371/journal.pone.0073356

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