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Concomitant Tumor Expression of EGFR and TATI/SPINK1 Associates with Better Prognosis in Colorectal Cancer

BACKGROUND: Epidermal growth factor receptor (EGFR) activation plays a role in colorectal cancer (CRC) carcinogenesis, and anti-EGFR drugs are used in treatment of advanced CRC. One of the EGFR ligands is tumor-associated trypsinogen inhibitor TATI, also called serine protease inhibitor Kazal type1...

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Detalles Bibliográficos
Autores principales: Koskensalo, Selja, Louhimo, Johanna, Hagström, Jaana, Lundin, Mikael, Stenman, Ulf-Håkan, Haglund, Caj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3808372/
https://www.ncbi.nlm.nih.gov/pubmed/24204699
http://dx.doi.org/10.1371/journal.pone.0076906