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Monoacylglycerol Lipase (MAGL) Inhibition Attenuates Acute Lung Injury in Mice

Endocannabinoid signaling is terminated by enzymatic hydrolysis, a process that, for 2-Arachidonoylglycerol (2-AG), is mediated by monoacylglycerol lipase (MAGL). The piperidine carbamate, 4-​nitrophenyl- ​4-​(dibenzo[d] [1,3]dioxol-​5-​yl (hydroxy) methyl) piperidine- 1-​carboxylate (JZL184), is a...

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Detalles Bibliográficos
Autores principales: Costola-de-Souza, Carolina, Ribeiro, Alison, Ferraz-de-Paula, Viviane, Calefi, Atilio Sersun, Aloia, Thiago Pinheiro Arrais, Gimenes-Júnior, João Antonio, de Almeida, Vinicius Izidio, Pinheiro, Milena Lobão, Palermo-Neto, João
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3808422/
https://www.ncbi.nlm.nih.gov/pubmed/24204926
http://dx.doi.org/10.1371/journal.pone.0077706