Properties of MHC Class I Presented Peptides That Enhance Immunogenicity

T-cells have to recognize peptides presented on MHC molecules to be activated and elicit their effector functions. Several studies demonstrate that some peptides are more immunogenic than others and therefore more likely to be T-cell epitopes. We set out to determine which properties cause such diff...

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Detalles Bibliográficos
Autores principales: Calis, Jorg J. A., Maybeno, Matt, Greenbaum, Jason A., Weiskopf, Daniela, De Silva, Aruna D., Sette, Alessandro, Keşmir, Can, Peters, Bjoern
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3808449/
https://www.ncbi.nlm.nih.gov/pubmed/24204222
http://dx.doi.org/10.1371/journal.pcbi.1003266

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3808449/
https://www.ncbi.nlm.nih.gov/pubmed/24204222
http://dx.doi.org/10.1371/journal.pcbi.1003266

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