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Global cellular response to chemotherapy-induced apoptosis

How cancer cells globally struggle with a chemotherapeutic insult before succumbing to apoptosis is largely unknown. Here we use an integrated systems-level examination of transcription, translation, and proteolysis to understand these events central to cancer treatment. As a model we study myeloma...

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Detalles Bibliográficos
Autores principales: Wiita, Arun P, Ziv, Etay, Wiita, Paul J, Urisman, Anatoly, Julien, Olivier, Burlingame, Alma L, Weissman, Jonathan S, Wells, James A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3808542/
https://www.ncbi.nlm.nih.gov/pubmed/24171104
http://dx.doi.org/10.7554/eLife.01236