Increased expression of Drosophila Sir 2 extends life span in a dose-dependent manner

Sir2, a member of the sirtuin family of protein acylases, deacetylates lysine residues within many proteins and is associated with lifespan extension in a variety of model organisms. Recent studies have questioned the positive effects of Sir2 on lifespan in Drosophila. Several studies have shown tha...

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Detalles Bibliográficos
Autores principales: Whitaker, Rachel, Faulkner, Shakeela, Miyokawa, Reika, Burhenn, Lucas, Henriksen, Mark, Wood, Jason G., Helfand, Stephen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3808700/
https://www.ncbi.nlm.nih.gov/pubmed/24036492

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3808700/
https://www.ncbi.nlm.nih.gov/pubmed/24036492

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