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Increased expression of Drosophila Sir 2 extends life span in a dose-dependent manner
Sir2, a member of the sirtuin family of protein acylases, deacetylates lysine residues within many proteins and is associated with lifespan extension in a variety of model organisms. Recent studies have questioned the positive effects of Sir2 on lifespan in Drosophila. Several studies have shown tha...
Autores principales: | Whitaker, Rachel, Faulkner, Shakeela, Miyokawa, Reika, Burhenn, Lucas, Henriksen, Mark, Wood, Jason G., Helfand, Stephen L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3808700/ https://www.ncbi.nlm.nih.gov/pubmed/24036492 |
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