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Neuroprotective Properties of a Novel Non-Thiazoledinedione Partial PPAR-γ Agonist against MPTP

Activation of the peroxisome proliferator activated receptor-gamma (PPAR)-γ is proposed as a neuroprotective strategy to treat neurodegenerative disorders. In this study, we examined if LSN862 (LSN), a novel non-thiazoledinedione partial PPAR-γ agonist, was neuroprotective in a mouse model of Parkin...

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Detalles Bibliográficos
Autores principales: Swanson, Christine R., Du, Eric, Johnson, Delinda A., Johnson, Jeffrey A., Emborg, Marina E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3808726/
https://www.ncbi.nlm.nih.gov/pubmed/24223584
http://dx.doi.org/10.1155/2013/582809