MicroRNA-based strategy to mitigate the risk of gain-of-function influenza studies

Recent gain-of-function studies in influenza A virus H5N1 strains revealed that as few as three-amino-acid changes in the hemagglutinin protein confer the capacity for viral transmission between ferrets(1,2). As transmission between ferrets is considered a surrogate indicator of transmissibility bet...

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Detalles Bibliográficos
Autores principales: Langlois, Ryan A, Albrecht, Randy A, Kimble, Brian, Sutton, Troy, Shapiro, Jillian S, Finch, Courtney, Angel, Matthew, Chua, Mark A, Gonzalez-Reiche, Ana Silvia, Xu, Kemin, Perez, Daniel, García-Sastre, Adolfo, tenOever, Benjamin R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3808852/
https://www.ncbi.nlm.nih.gov/pubmed/23934176
http://dx.doi.org/10.1038/nbt.2666

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3808852/
https://www.ncbi.nlm.nih.gov/pubmed/23934176
http://dx.doi.org/10.1038/nbt.2666

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