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Cancer cell metabolism: implications for therapeutic targets

Cancer cell metabolism is characterized by an enhanced uptake and utilization of glucose, a phenomenon known as the Warburg effect. The persistent activation of aerobic glycolysis in cancer cells can be linked to activation of oncogenes or loss of tumor suppressors, thereby fundamentally advancing c...

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Detalles Bibliográficos
Autores principales: Jang, Miran, Kim, Sung Soo, Lee, Jinhwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3809361/
https://www.ncbi.nlm.nih.gov/pubmed/24091747
http://dx.doi.org/10.1038/emm.2013.85