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A Guide RNA Sequence Design Platform for the CRISPR/Cas9 System for Model Organism Genomes

Cas9/CRISPR has been reported to efficiently induce targeted gene disruption and homologous recombination in both prokaryotic and eukaryotic cells. Thus, we developed a Guide RNA Sequence Design Platform for the Cas9/CRISPR silencing system for model organisms. The platform is easy to use for gRNA d...

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Detalles Bibliográficos
Autores principales: Ma, Ming, Ye, Adam Y., Zheng, Weiguo, Kong, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3809372/
https://www.ncbi.nlm.nih.gov/pubmed/24199189
http://dx.doi.org/10.1155/2013/270805