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RAF and antioxidants prevent cell death induction after growth factor abrogation through regulation of Bcl-2 proteins()
We have shown previously that mitochondrial ROS production is essential to turn growth factor (GF) removal into cell death. Activated RAF, AKT, Bcl-2 and antioxidants protected equally well against ROS accumulation and subsequent death. Here we investigated whether protection by survival signaling a...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3809515/ https://www.ncbi.nlm.nih.gov/pubmed/23933517 http://dx.doi.org/10.1016/j.yexcr.2013.07.029 |