Cargando…

RAF and antioxidants prevent cell death induction after growth factor abrogation through regulation of Bcl-2 proteins()

We have shown previously that mitochondrial ROS production is essential to turn growth factor (GF) removal into cell death. Activated RAF, AKT, Bcl-2 and antioxidants protected equally well against ROS accumulation and subsequent death. Here we investigated whether protection by survival signaling a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Koziel, Katarzyna, Smigelskaite, Julija, Drasche, Astrid, Enthammer, Marion, Ashraf, Muhammad Imtiaz, Khalid, Sana, Troppmair, Jakob
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Academic Press 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3809515/ https://www.ncbi.nlm.nih.gov/pubmed/23933517 http://dx.doi.org/10.1016/j.yexcr.2013.07.029

Ejemplares similares

cJun N-terminal kinase (JNK) phosphorylation of serine 36 is critical for p66Shc activation
por: Khalid, Sana, et al.
Publicado: (2016)

A p38MAPK/MK2 signaling pathway leading to redox stress, cell death and ischemia/reperfusion injury
por: Ashraf, Muhammad Imtiaz, et al.
Publicado: (2014)

Cytoplasmic signaling in the control of mitochondrial uproar?
por: Hermann, Martin, et al.
Publicado: (2008)

Negative regulation of mitochondrial VDAC channels by C-Raf kinase
por: Le Mellay, Véronique, et al.
Publicado: (2002)

The Human G Protein-Coupled ATP Receptor P2Y(11) Is Associated With IL-10 Driven Macrophage Differentiation
por: Gruenbacher, Georg, et al.
Publicado: (2019)

Novel Insights into the PKCβ-dependent Regulation of the Oxidoreductase p66Shc
por: Haller, Martina, et al.
Publicado: (2016)

Use of a recombinant Salmonella enterica serovar Typhimurium strain expressing C-Raf for protection against C-Raf induced lung adenoma in mice
por: Gentschev, Ivaylo, et al.
Publicado: (2005)

Mutation-oriented profiling of autoinhibitory kinase conformations predicts RAF inhibitor efficacies
por: Mayrhofer, Johanna E., et al.
Publicado: (2020)

Subcutaneous administration of a neutralizing IL‐1β antibody prolongs limb allograft survival
por: Hautz, Theresa, et al.
Publicado: (2018)

Induction and abrogation of unresponsiveness in nude mouse cells
Publicado: (1976)

Neuroprotective Action of Cycloheximide Involves Induction of Bcl-2 and Antioxidant Pathways
por: Furukawa, Katsutoshi, et al.
Publicado: (1997)

The oxidoreductase p66Shc acts as tumor suppressor in BRAFV600E‐transformed cells
por: Furlan, Tobias, et al.
Publicado: (2018)

Rigosertib-Activated JNK1/2 Eliminate Tumor Cells through p66Shc Activation
por: Günther, Julia K., et al.
Publicado: (2020)

RAF inhibitors promote RAS-RAF interaction by allosterically disrupting RAF autoinhibition
por: Jin, Ting, et al.
Publicado: (2017)

Acetylation of the Proto-Oncogene EVI1 Abrogates Bcl-xL Promoter Binding and Induces Apoptosis
por: Pradhan, Anjan Kumar, et al.
Publicado: (2011)

Interferon-α Abrogates Tolerance Induction by Human Tolerogenic Dendritic Cells
por: Bacher, Nicole, et al.
Publicado: (2011)

Computational Evaluation of Abrogation of HBx-Bcl-xL Complex with High-Affinity Carbon Nanotubes (Fullerene) to Halt the Hepatitis B Virus Replication
por: Khan, Abbas, et al.
Publicado: (2021)

Sonic hedgehog inhibitors prevent colitis-associated cancer via orchestrated mechanisms of IL-6/gp130 inhibition, 15-PGDH induction, Bcl-2 abrogation, and tumorsphere inhibition
por: Kangwan, Napapan, et al.
Publicado: (2015)

A personalized molecular approach in multiple myeloma: the possible use of RAF/RAS/MEK/ERK and BCL-2 inhibitors
por: Raimondi, Vincenzo, et al.
Publicado: (2022)

Targeting the Raf kinases in human cancer: the Raf dimer dilemma
por: Durrant, David E, et al.
Publicado: (2018)

Antioxidant and skin-whitening effects of aerial part of Euphorbia supina Raf. Extract
por: Kang, Sa-Haeng, et al.
Publicado: (2018)

Experimental granulomatous colitis in mice is abrogated by induction of TGF-beta-mediated oral tolerance
Publicado: (1996)

Molecular Characterization of Lung Dysplasia Induced by c-Raf-1
por: Rohrbeck, Astrid, et al.
Publicado: (2009)

Selective inhibition of protein secretion by abrogating receptor–coat interactions during ER export
por: Gomez-Navarro, Natalia, et al.
Publicado: (2022)

“RAF” neighborhood: Protein–protein interaction in the Raf/Mek/Erk pathway
por: Cseh, Botond, et al.
Publicado: (2014)

Smooth Muscle-Specific BCL6+/− Knockout Abrogates Sex Bias in Chronic Hypoxia-Induced Pulmonary Arterial Hypertension in Mice
por: Yang, Yang-Ming, et al.
Publicado: (2018)

A Model of Induction of Cerebellar Long-Term Depression Including RKIP Inactivation of Raf and MEK
por: Hepburn, Iain, et al.
Publicado: (2017)

Targeted Induction of Interferon-λ in Humanized Chimeric Mouse Liver Abrogates Hepatotropic Virus Infection
por: Nakagawa, Shin-ichiro, et al.
Publicado: (2013)

Tropifexor‐Mediated Abrogation of Steatohepatitis and Fibrosis Is Associated With the Antioxidative Gene Expression Profile in Rodents
por: Hernandez, Eloy D., et al.
Publicado: (2019)

Regulation of cellular proliferation, differentiation and cell death by activated Raf
por: Thiel, Gerald, et al.
Publicado: (2009)

Tolerance induction in B lymphocytes but thymus-dependent antigens. T cells may abrogate B-cell tolerance induction by prevent an antibody response
Publicado: (1975)

RAF inhibitors transactivate RAF dimers and ERK signaling in cells with wild-type BRAF
por: Poulikakos, Poulikos I., et al.
Publicado: (2010)

Mixed lineage kinases activate MEK independently of RAF to mediate resistance to RAF inhibitors
por: Marusiak, Anna A., et al.
Publicado: (2014)

Molecular recognition of RAS/RAF complex at the membrane: Role of RAF cysteine-rich domain
por: Travers, Timothy, et al.
Publicado: (2018)

Inhibitors of Bcl-2 and Bruton’s tyrosine kinase synergize to abrogate diffuse large B-cell lymphoma growth in vitro and in orthotopic xenotransplantation models
por: Bertram, Katrin, et al.
Publicado: (2021)

Effective tumor cell abrogation via Venetoclax-mediated BCL-2 inhibition in KMT2A-rearranged acute B-lymphoblastic leukemia
por: Richter, Anna, et al.
Publicado: (2022)

Activation of an early feedback survival loop involving phospho-ErbB3 is a general response of melanoma cells to RAF/MEK inhibition and is abrogated by anti-ErbB3 antibodies
por: Fattore, Luigi, et al.
Publicado: (2013)

Raf-1 regulates migration
por: Tuma, Rabiya S.
Publicado: (2005)

Resistance to RAF inhibitors revisited
por: Hartsough, Edward, et al.
Publicado: (2013)

Arabidopsis Raf-Like Kinase Raf10 Is a Regulatory Component of Core ABA Signaling
por: Nguyen, Quy Thi Cam, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_9tkal4l5mo1iec50s2ng1p8565