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Sodium channel SCN8A (Na(v)1.6): properties and de novo mutations in epileptic encephalopathy and intellectual disability
The sodium channel Na(v)1.6, encoded by the gene SCN8A, is one of the major voltage-gated channels in human brain. The sequences of sodium channels have been highly conserved during evolution, and minor changes in biophysical properties can have a major impact in vivo. Insight into the role of Na(v)...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3809569/ https://www.ncbi.nlm.nih.gov/pubmed/24194747 http://dx.doi.org/10.3389/fgene.2013.00213 |